Recombinant Rab6-GTP (Gln72Leu-Mutant) anticorps

N° du produit ABIN5564231

Cet anticorps Human Monoclonal détecte spécifiquement dans ICC. Il présente une réactivité envers Drosophila melanogaster, Humain et Souris.

Aperçu rapide pour Recombinant Rab6-GTP (Gln72Leu-Mutant) anticorps (ABIN5564231)

Antigène: Rab6-GTP

Type d'anticorp: Recombinant Antibody

Reactivité: Drosophila melanogaster, Humain, Souris

Hôte: Human

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunocytochemistry (ICC)

Clone: AA2

Détail du produit

Épitope: Gln72Leu-Mutant

Specificité: Recognizes human, mouse and Drosophila GTP-bound Rab6a and Rab6b and mutant Rab6Q72L.

Réactivité croisée: Mouche des fruits (Drosophila melanogaster), Humain, Souris

Réactivité croisée (Details): Does not detect Rab6•GDP.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant Rab6AQ72L, a GTP-locked mutant of Rab6A in which Gln72 is replaced by Leu.

Isotype: IgG2

Information d'application

Commentaires:

anti-Rab6-GTP monoclonal antibody (recombinant) (AA2) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain. anti-Rab6-GTP monoclonal antibody (recombinant) (AA2) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détail du antigène

Antigène: Rab6-GTP

Sujet: Rab6 is involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).

UniProt: P20340